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NEUMED PRODUCT INTRODUCTION
PRODUCTS
PRODUCT OVERVIEW

PEONY EXTRACT COMPLEX [HT074]

AN MFDS-RECOGNIZED FUNCTIONAL INGREDIENT THAT MAY HELP SUPPORT STOMACH HEALTH BY PROTECTING THE GASTRIC MUCOSA

MFDS Recognition No. 2020-3 · Human Study in Korean Participants
Korean Registered Patent No. 10-1756149 · NeuQure™ Quality Management

FOCUSED ON GASTRIC MUCOSAL PROTECTION, NOT ACID SUPPRESSION

HT074 is a standardized complex natural product ingredient developed from Peony and Inula flower. It has been recognized by the MFDS for the functionality of “may help support stomach health by protecting the gastric mucosa.” NeuMed has studied stomach health not simply as a matter of gastric acid control, but from the perspective of gastric mucosal protection and antioxidant defense. In a human study involving 144 sub-healthy Korean adults, HT074 was associated with approximately 30% improvement in upper abdominal discomfort within two weeks of intake, supporting its role as a gastric mucosa-protecting functional ingredient.

WHAT MAKES HT074 SPECIAL
FEATURES

HT074’s Dual Defense Approach: Gastric Mucosal Protection and Stomach Comfort

UP TO 98%

Protection Against Gastric Mucosal Damage

Inhibition of gastric mucosal damage was observed in five irritation models, including alcohol, stress, and NSAID-induced models.

WITHIN 2 WEEKS

Improvement in Upper Abdominal Discomfort

Significant improvement in upper abdominal discomfort was observed in a human study.

DUAL DEFENSE

Mucus Layer Support and Antioxidant Action

HT074 supports stomach wall defense by helping maintain the gastric mucus layer and antioxidant activity.

144 Participants

1 Patent

5 Models

700mg

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 PROBLEMS IN STOMACH HEALTH
PROBLEM

Why can stomach discomfort continue even when acid is controlled?

Around one in five adults worldwide experiences functional dyspepsia, such as upper abdominal discomfort, bloating, or heartburn, which can affect daily life and sleep. Many approaches focus on controlling gastric acid. However, acid control alone may not fully address stomach discomfort if the gastric mucosa remains vulnerable. A broader approach to stomach health looks beyond acid suppression and focuses on protecting the gastric mucosa, supporting the mucus layer, and reducing oxidative stress.

PROBLEM. 01

1 IN 5
ADULTS


Functional Dyspepsia

A common stomach health concern
that can affect daily life and sleep

PROBLEM. 02

LIMITS OF ACID SUPPRESSION


Acid control alone
may not be enough

The gastric mucosa also needs
protective support

PROBLEM. 03

GASTRIC MUCOSAL PROTECTION


A Broader Approach
to Stomach Health

Supporting the mucus layer and
antioxidant defense to help protect the stomach

HT074 DEVELOPMENT STORY
STORY

NeuMed looked beyond gastric acid suppression
and focused on protecting the gastric mucosa.

2011
BEGINNING OF GASTRIC MUCOSAL PROTECTION RESEARCH

Using the iMED platform, NeuMed explored natural materials that could help protect the gastric mucosa beyond simply suppressing gastric acid. Through this process, NeuMed identified the potential of Peony and Inula flower.


2020
MFDS
RECOGNITION

HT074 was evaluated in a human study involving 144 adults and was recognized by the MFDS in 2020 for its functionality of helping support stomach health by protecting the gastric mucosa.


PRESENT
EXPANSION AS A STOMACH HEALTH INGREDIENT

HT074, a standardized complex ingredient developed from Peony and Inula flower, has been applied to various health functional foods in Korea, supported by NeuMed’s quality management and stable supply system.


HOW HT074 HELPS PROTECT THE STOMACH
HOW IT WORKS

HT074’s Dual Defense Mechanism for Gastric Mucosal Protection

Stomach discomfort can begin when various irritants, including gastric acid, alcohol, stress, and NSAIDs, weaken the protective barrier of the gastric mucosa and increase oxidative stress. HT074 has been studied for its potential to help protect the gastric mucosa by supporting the gastric mucus layer and antioxidant defense.

STEP. 01

STRENGTHENING THE GASTRIC MUCUS LAYER


Increased Gastric
Mucus Secretion

HT074 has been studied in relation to factors involved in forming the protective gastric mucus layer, helping reduce direct contact between gastric acid, external irritants, and the stomach wall.

STEP. 02

ANTIOXIDANT
DEFENSE


Reduced
Oxidative Stress

HT074 has been studied in relation to antioxidant enzyme activity, helping reduce reactive oxygen species associated with gastric mucosal damage. 

STEP. 03

INHIBITION OF
GASTRIC DAMAGE


Reduced Gastric
Mucosal Damage

Through mucus layer support and antioxidant defense, HT074 has been studied for its potential to help reduce gastric mucosal damage under irritation conditions such as alcohol, stress, and NSAIDs.

30% Increase

1.6× increase in protective proteins
1.8× increase in protective factors 


40% Increase

Helps reduce excess reactive oxygen species
Helps suppress damaged-cell death 


Up to 98% Inhibition

Observed in five irritation models
including alcohol, stress, and NSAIDs 


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EVIDENCE
HUMAN
CLINICAL TRIALS

Evaluated for efficacy and safety in Korean adults with upper abdominal discomfort

In an 8-week randomized, placebo-controlled human study involving 144 adults, the group taking HT074 700 mg/day showed the following results.

PRIMARY EFFICACY INDICATOR ·
UPPER ABDOMINAL DISCOMFORT

APPROXIMATELY
30% REDUCTION


Improvement observed within two weeks

In the high-dose group, upper abdominal discomfort measured by NDI-K decreased by approximately 30% within two weeks. By week 8, the GSRS heartburn score decreased by more than half from baseline.

SECONDARY EFFICACY INDICATOR ·
QUALITY OF LIFE

60% GREATER
 IMPROVEMENT


Quality-of-life improvement compared with the control group

At week 4, the total FD-QOL quality-of-life score improved approximately 60% more than the control group, with notable improvement in vitality-related items such as “lack of energy.”

WHO IS HT074 FOR?
BENEFITS

For consumers and B2B partners seeking a scientifically supported stomach health ingredient

HT074 is an MFDS-recognized functional ingredient for stomach health that has been evaluated in an 8-week randomized, double-blind, placebo-controlled human study involving 144 Korean adults. The study assessed upper abdominal discomfort and stomach-health-related quality of life.

CONSUMERS

FOR THOSE LOOKING
FOR STOMACH
HEALTH SUPPORT


Stomach Comfort
Within 2 Weeks

Upper abdominal discomfort was reduced within two weeks in the human study. 


Support Against
Gastric Irritation

HT074 has been studied in irritation models involving alcohol, stress, and NSAIDs, showing its potential to help protect the gastric mucosa.


Quality of Life Support

Stomach-health-related quality of life improved in the human study, including vitality-related items such as “lack of energy.”


Botanical Ingredient

HT074 is a natural product-based ingredient developed from Peony and Inula flower.

B2B PARTNERS AND BRANDS

FOR BRANDS SEEKING
A DIFFERENTIATED
STOMACH HEALTH
INGREDIENT


Differentiation from
Acid Suppression

HT074 offers a stomach health positioning focused on gastric mucosal protection, rather than acid suppression alone.


Human Study
Data Available

An 8-week human study involving 144 adults and data from five irritation models are available as technical materials.


Daily Intake of 700 mg

HT074 is designed for a daily intake of 700 mg, supporting convenient product planning.


Research-Based
Ingredient Development

HT074 was developed through NeuMed’s iMED platform, connecting traditional botanical knowledge with modern scientific validation.

HT074 RAW MATERIALS
HT074 BOTANICAL INGREDIENTS

NeuQure™ Quality Management from Botanical Origin to Production Region

HT074 is NeuMed’s botanical complex extract developed from Peony and Inula flower. Based on the NeuQure™ Botanical Quality Assurance System, NeuMed manages the botanical origin, production region, cultivation environment, extraction process, and marker compounds of the source plants to ensure consistent quality for HT074.

GASTRIC MUCOSAL SUPPORT
· BLOOD FLOW SUPPORT

PEONY


Traditional Records

Donguibogam describes Peony as an herb traditionally used to nourish the blood, relieve spasms, and ease abdominal discomfort. It has often been used in prescriptions related to the stomach and abdomen.


Modern Research

Paeoniflorin, a key component of Peony, has been studied in relation to blood flow and PGE₂, a gastric protective factor, in gastric cells. It has also been studied for its antioxidant activity related to reactive oxygen species and gastric mucosal irritation.

ANTIOXIDANT DEFENSE
· STOMACH COMFORT SUPPORT

INULA FLOWER


Traditional Records

Shennong Bencaojing describes Inula flower as an herb traditionally used to calm the stomach and relieve nausea. It has long been used in relation to digestive discomfort.


Modern Research

1-O-acetylbritannilactone, a characteristic component of Inula flower, has been studied in relation to antioxidant enzyme activity, including SOD and GSH, which helps support gastric mucosal protection. It has also been studied in relation to gastric acid-related irritation and stomach comfort.

RECOGNITION · PATENTS · QUALITY
SCIENTIFIC RELIABILITY

HT074’s scientific reliability backed by MFDS recognition, a Korean registered patent, and quality management

Patents: Korean registered patent covering the composition and manufacturing process of the Peony and Inula flower complex extra
Quality Management: Stepwise quality standards applied from raw material sourcing to finished ingredient

KOREA MINISTRY OF FO
AND DRUG SAFETY

INDIVIDUALLY RECOGNIZED FUNCTIONAL INGREDIENT


Recognized for helping support stomach
 health by protecting the gastric mucosa.
MFDS Recognition No. 2020-3.

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INGREDIENT SUPPLY INQUIRIES
CONTACT

Start a new stomach health product with HT074, an MFDS-recognized functional ingredient for gastric mucosal protection. HT074 can be supplied as a standardized functional ingredient for brands developing stomach health products in various formats, including tablets, capsules, gummies, powders, and food applications. 

Based on human study data involving 144 participants, gastric mucosal protection research, patent documentation, and quality management, NeuMed supports partner brands seeking a differentiated stomach health ingredient.

PRODUCT OVERVIEW

PEONY EXTRACT COMPLEX [HT074]

AN MFDS-RECOGNIZED FUNCTIONAL INGREDIENT THAT MAY HELP SUPPORT STOMACH HEALTH BY PROTECTING THE GASTRIC MUCOSA

MFDS Recognition No. 2020-3 · Human Study in Korean Participants
Korean Registered Patent No. 10-1756149 · NeuQure™ Quality Management

FOCUSED ON GASTRIC MUCOSAL PROTECTION, NOT ACID SUPPRESSION

HT074 is a standardized complex natural product ingredient developed from Peony and Inula flower. It has been recognized by the MFDS for the functionality of “may help support stomach health by protecting the gastric mucosa.” NeuMed has studied stomach health not simply as a matter of gastric acid control, but from the perspective of gastric mucosal protection and antioxidant defense.

In a human study involving 144 sub-healthy Korean adults, HT074 was associated with approximately 30% improvement in upper abdominal discomfort within two weeks of intake, supporting its role as a gastric mucosa-protecting functional ingredient.

WHAT MAKES HT074 SPECIAL
FEATURES

HT074’s Dual Defense Approach: Gastric Mucosal Protection and Stomach Comfort

UP TO 98%

Protection Against
Gastric Mucosal
Damage

Inhibition of gastric mucosal damage
was observed in five irritation models,
including alcohol, stress,
and NSAID-induced models.

WITHIN 2 WEEKS

Improvement
in Upper Abdominal
Discomfort

Significant improvement
in upper abdominal discomfort
was observed in a human study.

DUAL DEFENSE

Mucus Layer Support
and Antioxidant
Action

HT074 supports stomach wall defense
by helping maintain the gastric mucus layer
and antioxidant activity.

mobile background
PROBLEMS IN STOMACH HEALTH
PROBLEM

Why can stomach discomfort continue even when acid is controlled?

Around one in five adults worldwide experiences functional dyspepsia,
such as upper abdominal discomfort, bloating, or heartburn, which can affect daily life and sleep.

Many approaches focus on controlling gastric acid. However,
acid control alone may not fully address stomach discomfort if the gastric mucosa remains vulnerable.

A broader approach to stomach health looks beyond acid suppression
and focuses on protecting the gastric mucosa, supporting the mucus layer, and reducing oxidative stress.

PROBLEM. 01

1 IN 5
ADULTS


Functional
Dyspepsia

A common stomach health concern
that can affect daily life and sleep

PROBLEM. 02

LIMITS OF ACID
SUPPRESSION


Acid control alone
may not be enough

The gastric mucosa also needs
protective support

PROBLEM. 03

GASTRIC MUCOSAL
PROTECTION


A Broader Approach
to Stomach Health

Supporting the mucus layer and
antioxidant defense to help protect the stomach

HT074 DEVELOPMENT STORY
STORY

NeuMed looked beyond gastric acid suppression
and focused on protecting the gastric mucosa.

2011
BEGINNING OF GASTRIC MUCOSAL PROTECTION RESEARCH

Using the iMED platform, NeuMed explored
natural materials that could help protect 
the gastric mucosa beyond simply suppressing

gastric acid. Through this process, NeuMed
identified the potential of Peony and Inula flower.


2020
MFDS
RECOGNITION

HT074 was evaluated in
a human study involving
144 adults and was recognized by the MFDS
in 2020 for its functionality of helping support
stomach health by protecting the gastric mucosa.


PRESENT
EXPANSION AS A STOMACH
HEALTH INGREDIENT

HT074, a standardized complex ingredient
developed from Peony and Inula flower, has
been applied to various health functional foods
in Korea, 
supported by NeuMed’s quality
management and stable supply system.


HOW HT074 HELPS PROTECT THE STOMACH
HOW IT WORKS

HT074’s Dual Defense Mechanism for Gastric Mucosal Protection

Stomach discomfort can begin when various irritants, including gastric acid, alcohol, stress, and NSAIDs, weaken
the protective barrier of the gastric mucosa and increase oxidative stress.

HT074 has been studied for its potential to help protect
the gastric mucosa by supporting the gastric mucus layer and antioxidant defense.

STEP. 01

STRENGTHENING
THE GASTRIC

MUCUS LAYER


Increased Gastric
Mucus Secretion

HT074 has been studied in relation to factors
involved in forming the protective
gastric mucus layer, helping reduce direct
contact between gastric acid,
external irritants, and the stomach wall.

STEP. 02

ANTIOXIDANT
DEFENSE



Reduced
Oxidative Stress

HT074 has been studied in relation
to antioxidant enzyme activity,
helping reduce reactive oxygen species
associated with gastric mucosal damage.

STEP. 03

INHIBITION
OF GASTRIC
DAMAGE


Reduced Gastric
Mucosal Damage

Through mucus layer support and
antioxidant defense, HT074 has been studied
for its potential to help reduce gastric mucosal
damage under irritation conditions
such as alcohol, stress, and NSAIDs.

30Increase

1.6× increase in protective proteins
1.8× increase in protective factors 


40% Increase

Helps reduce excess reactive oxygen species
Helps suppress damaged-cell death 


Up to 98% Inhibition

Observed in five irritation models
including alcohol, stress, and NSAIDs 


mobile background
EVIDENCE
HUMAN CLINICAL TRIALS

Evaluated for efficacy and safety in Korean adults
with upper abdominal discomfort

In an 8-week randomized, 
placebo-controlled human study involving 144 adults, 
the group taking HT074 700 mg/day showed the following results.

PRIMARY EFFICACY INDICATOR · 
UPPER ABDOMINAL DISCOMFORT

APPROXIMATELY
30% REDUCTION


Improvement observed
within two weeks

In the high-dose group, upper abdominal discomfort measured by NDI-K
decreased by approximately 30% within two weeks. By week 8, the GSRS
heartburn score decreased by more than half from baseline.

SECONDARY EFFICACY INDICATOR · 
QUALITY OF LIFE

60% GREATER
IMPROVEMENT


Quality-of-life improvement compared
with the control group

At week 4, the total FD-QOL quality-of-life score
improved approximately 60% more than the control group,
with notable improvement in vitality-related items such as “lack of energy.”

WHO IS HT074 FOR?
BENEFITS

For consumers and B2B partners seeking a scientifically supported stomach health ingredient

HT074 is an MFDS-recognized functional ingredient for stomach health that has been evaluated in an 8-week randomized, double-blind, placebo-controlled human study involving 144 Korean adults. The study assessed upper abdominal discomfort and stomach-health-related quality of life.

CONSUMERS

FOR THOSE LOOKING
FOR STOMACH
HEALTH SUPPORT


Stomach Comfort Within 2 Weeks

Upper abdominal discomfort was
reduced within two weeks in the human study.


Support Against Gastric Irritation

HT074 has been studied in irritation models involving alcohol, stress,
and NSAIDs, showing its potential to help protect the gastric mucosa.


Quality of Life Support

Stomach-health-related quality of life improved in the human study,
including vitality-related items such as “lack of energy.”


Botanical Ingredient

HT074 is a natural product-based
ingredient developed from Peony and Inula flower.

B2B PARTNERS AND BRANDS

FOR BRANDS SEEKING
A DIFFERENTIATED STOMACH
HEALTH INGREDIENT


Differentiation from Acid Suppression

HT074 offers a stomach health positioning focused on gastric
mucosal protection, rather than acid suppression alone.


Human Study Data Available

An 8-week human study involving 144 adults and
data from five irritation models are available as technical materials.


Daily Intake of 700 mg

HT074 is designed for a daily intake of 700 mg,
supporting convenient product planning.


Research-Based Ingredient Development

HT074 was developed through NeuMed’s iMED platform,
connecting traditional botanical knowledge with modern scientific validation.

HT074 RAW MATERIALS
HT074 BOTANICAL INGREDIENTS 

NeuQure™ Quality Management from Botanical Origin to Production Region

HT074 is NeuMed’s botanical complex extract developed from Peony and Inula flower. Based on the NeuQure™ Botanical Quality Assurance System, NeuMed manages the botanical origin, production region, cultivation environment, extraction process, and marker compounds of the source plants to ensure consistent quality for HT074.

GASTRIC MUCOSAL SUPPORT · BLOOD FLOW SUPPORT

PEONY


Traditional Records

Donguibogam describes Peony as an herb traditionally used to nourish the blood, relieve spasms, and ease abdominal discomfort. It has often been used in prescriptions related to the stomach and abdomen.


Modern Research

Paeoniflorin, a key component of Peony, has been studied in relation to blood flow and PGE₂, a gastric protective factor, in gastric cells. It has also been studied for its antioxidant activity related to reactive oxygen species and gastric mucosal irritation.

ANTIOXIDANT DEFENSE · STOMACH COMFORT SUPPORT

INULA FLOWER


Traditional Records

Shennong Bencaojing describes Inula flower as an herb traditionally used to calm the stomach and relieve nausea. It has long been used in relation to digestive discomfort.


Modern Research

1-O-acetylbritannilactone, a characteristic component of Inula flower, has been studied in relation to antioxidant enzyme activity, including SOD and GSH, which helps support gastric mucosal protection. It has also been studied in relation to gastric acid-related irritation and stomach comfort.

RECOGNITION · PATENTS · QUALITY
SCIENTIFIC RELIABILITY

HT074’s scientific reliability backed by MFDS recognition, a Korean registered patent, and quality management

Patents: Korean registered patent covering the composition and manufacturing process of the Peony and Inula flower complex extract
Quality Management: Stepwise quality standards applied from raw material sourcing to finished ingredient

KOREA MINISTRY OF FOOD
AND DRUG SAFETY

INDIVIDUALLY
RECOGNIZED
FUNCTIONAL INGREDIENT


Recognized for helping support stomach
health by protecting the gastric mucosa.
MFDS Recognition No. 2020-3. 

KOREAN
REGISTERED PATENT

PATENT 
NO. 10-1756149



Patent protection for the extraction,
concentration, and standardization process
of the Peony and Inula flower complex extract 

QUALITY
MANAGEMENT

GMP-BASED THREE-STEP QUALITY TESTING


Manufacturer analysis, NeuMed in-house analysis, and third-party accredited laboratory analysis are conducted to help verify ingredient quality, purity, and stability.

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INGREDIENT SUPPLY INQUIRIES
CONTACT

Start a new stomach health product with HT074, an MFDS-recognized functional ingredient for gastric mucosal protection. HT074 can be supplied as a standardized functional ingredient for brands developing stomach health products in various formats, including tablets, capsules, gummies, powders, and food applications. 

Based on human study data involving 144 participants, gastric mucosal protection research,
patent documentation, and quality management, NeuMed supports partner brands seeking
a differentiated stomach health ingredient.

COMPANY : NEUMED, Inc / CEO : Hocheol Kim 
TEL : +82-2-564-9140 / FAX : +82-2-564-9290

MAIL : sales@neumed.co.krBUSINESS LICENSE : 204-81-77134
ADD : 6F, 88 Imun-ro, Dongdaemun-gu, Seoul, Republic of Korea

4F, Seongsu SK V1 CENTER I, 48 Achasan-ro 17-gil, Seongdong-gu, Seoul, Republic of Korea

ⓒ 2026 NEUMED. ALL RIGHTS RESERVED.

COMPANY : NEUMED, Inc / CEO : Hocheol Kim 
TEL : +82-2-564-9140 / FAX : +82-2-564-9290

MAIL : sales@neumed.co.kr
BUSINESS LICENSE : 204-81-77134
ADD : 6F, 88 Imun-ro, Dongdaemun-gu,
Seoul, Republic of Korea

4F, Seongsu SK V1 CENTER I, 48 Achasan-ro
17-gil, Seongdong-gu, Seoul, Republic of Korea 

ⓒ 2026 NEUMED. ALL RIGHTS RESERVED.